Practical course Molecular Pharmacology

2018-2019
This course is offered in Dutch. Some of the descriptions may therefore only be available in Dutch.

Course Objective

The aim of this course is to get acquainted with the performance of
pharmacological assays and molecular biological techniques in the
laboratory. This course is linked to the course 'Molecular
Pharmacology' (XB_43001), addressing how drugs act on (patho)
physiological processes and pharmacological parameters.

Course Content

To study the pharmacological parameters of drugs cellular model systems
(mammalian cells) expressing drug targets of interest will be used.
During the practical work students will perform ligand-receptor
interaction studies, functional studies to determine ligand potency and
efficacy (e.g. G protein signaling, beta-arrestin recruitment) and
antagonistic properties of compounds (biosensor assay). Moreover, they
will also get acquainted with the use of molecular biological
techniques. This practical work will be accompanied by background
lectures (molecular pharmacology XB-43001), exercises to determine
pharmacological parameters and data analysis and reporting.

Teaching Methods

• Laboratory instructions
• Assignments

Method of Assessment

- Practical skills
- Measurement reports
- Theoretical and practical excercises

Entry Requirements

Before starting this course, the student must have passed the course
Cellulaire Biochemie (X_430624).

Literature

Rang & Dale’s Pharmacology 8th edition ISBN 978-0-7020-5362-7

Target Audience

2nd year students Pharmaceutical Sciences

Additional Information

This course needs to be taken together with the course Molecular
Pharmacology (XB_43001).
Attending excercise classes and practical work is mandatory.


Lecturers:
dr. Henry Vischer
dr. Marco Siderius

General Information

Course Code XB_43003
Credits 6 EC
Period P1
Course Level 200
Language of Tuition Dutch
Faculty Faculty of Science
Course Coordinator dr. H.F. Vischer
Examiner dr. H.F. Vischer
Teaching Staff dr. H.F. Vischer

Practical Information

You need to register for this course yourself

Last-minute registration is available for this course.

Teaching Methods Practical
Target audiences

This course is also available as: