Course ObjectiveThe overall aim of this course is to introduce the students to the basic
mathematical language required to describe atoms, electrons, and
molecules by means of the quantum mechanical description of matter. On
the one hand, the topics covered in the course are required to gain a
better understanding of the physical basis of important chemical
properties and physical reactions that appear frequently in a medical
context. On the other hand, this formalism also allows us to translate
quantum mechanical concepts into measurable quantities that can then be
used for medical applications, such as positron therapy or magnetic
nuclear resonance. In this course, we will therefore cover a number of
topics which range from fundamental quantum mechanics to the
corresponding applications in medical sciences.
Course ContentThe contents of the course are the following:
- It starts with a introduction to the quantum world, relevant for the
description of small objects like atoms, molecules, and electrons. This
involves presenting important concepts such as the wave-particle
duality, the De Broglie relations, and the Heisenberg uncertainty
principle of quantum mechanics.
- We will then move to present the fundamental equation of motion of
quantum theory, namely the Schroedinger equation, and apply it to a
number of important systems such as the particle in a box, the hydrogen
atom, the harmonic oscillator, and the hydrogen atom.
- The course will then explore next how quantum theory allows describing
the binding mechanisms between atoms that lead to the formation of
molecules. In this context, we will study the valence bond theory, the
molecular orbital theory, the concepts of hybridization in molecular
interactions, hydrogen bridges, and then Huckel theory for the
description of pi-bonds in polyatomic molecules.
- In the last part of the course we will consider the phenomena
associated to light-matter interactions in molecules, known as molecular
spectroscopy. We study vibrational modes in molecules, and how we can
characterise them, as well as the mechanism underlying phosphorescence
and photoluminescence. We emphasise their medical applications, such as
Photosensitive Therapy and Magnetic Nuclear Resonance.
Teaching MethodsLectures and tutorials, together with homework assignments
Method of AssessmentPartial (midterm) and Final Exam, as well as short assessments during
Entry RequirementsFysica en Medische Fysica 1/2
LiteraturePhysical Chemistry, 11th edition (Oxford University Press), by P.
Atkins, J. De Paula, J. Keeler.
|Language of Tuition||English|
|Faculty||Faculty of Science|
|Course Coordinator||dr. J. Rojo|
|Examiner||dr. J. Rojo|
dr. J. Rojo
You need to register for this course yourself
Last-minute registration is available for this course.
|Teaching Methods||Seminar, Lecture|
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