Major Research Project Theoretical Chemistry

2018-2019

Course Objective

The aim is to obtain experience in scientific research including the
design and execution of computational experiments and to critically
interpret and reflect on these results. The project will be conducted
within the field of theoretical (bio)chemistry in one of the following
settings:
- University or Academic hospital
- Research institute
- Company
The internship can be performed either within the Netherlands or abroad.

Course Content

The specific content of the project depends on the associated
supervisor(s), available projects at the host/location and the timing of
the internship, but generally deals with quantum chemical methods,
including Density Functional Theory (DFT). DFT calculations are used to
gain insights in chemical interactions, like reaction mechanisms that
lead to the synthesis of drugs, or the interactions of (drug) molecules
with DNA and/or proteins.

Attention will be paid to setting up new research/experiments, using
state-of-the-art computational techniques, analyzing computational
results and keeping adequate documentation.

Teaching Methods

Literature review, formulating a research question, conducting
experiments, keeping adequate documentation, analyzing data, reporting
on results in progress/group meetings, in a written thesis and final
presentation within the research group.

Method of Assessment

Academic attitude, execution, oral presentation, and written thesis

Entry Requirements

Entry requirements with respect to attained courses and number of
credits apply. See the Education and Examination regulations and the
internship manual Drug Discovery & Safety. For questions, consult the
internship coordinator well in advance (internships_sf.beta@vu.nl).

Literature

Starting literature will be provided by the supervisor. The first 1-2
weeks of the traineeship will be spent on literature reading and
preparation for the project.

Target Audience

Reseach variant of mDDS-CMCT, mDDS-DD&S

Additional Information

The standard length of a major internship is 42 EC (7 months). Extension
up to 60 EC (10 months) can be incorporated as part of the optional part
of the master program. Make sure you discuss your personal education
plan with your master (track) coordinator well in advance. See the
“Master Drug Discovery & Safety Internship manual” for more information
(rules, regulations, tips, etc.) on the internship process. This manual
can be found on the canvas community “Master Drug Discovery & Safety”.

Custom Course Registration

The number of internal (VU) internship positions is limited. Candidates are selected based on their motivation letter and CV in an application procedure. See the canvas site “Master Drug Discovery & Safety” for more information regarding this application procedure. Be aware that selection procedures exist for most external positions as well. Before the start of the project an internship agreement has to be signed by all involved parties and the project proposal has to be approved by the VU supervisor. See the “Master Drug Discovery & Safety Internship manual” for more information on the rules and regulation regarding internships. If after reading the manual you still have questions regarding the process related to internships, admission, approval, etc., please contact the internship coordinator via internships_sf.beta@vu.nl.

General Information

Course Code XM_0043
Credits 42 EC
Period Ac. Year (sept)
Course Level 600
Language of Tuition English
Faculty Faculty of Science
Course Coordinator dr. D.J. Scholten
Examiner dr. D.J. Scholten
Teaching Staff

Practical Information

You cannot register for this course yourself; your faculty's education office carries out registration

Target audiences

This course is also available as: