Course ObjectiveThe student has insight into and understanding of biological processes
fundamental in living cells.
The student has an overview of techniques used in Cell Biology and
understands their working principle.
The student can work with scientific literature.
Course ContentWe start with a brief repetition of basic Cell Biology and then go ahead
with in-depth discussion of modern Cell Biology, with a particular focus
on current and emerging experimental techniques. In Research Lectures,
current topics in Cell Biology will be discussed.
• General cell organization and function, protein, DNA and RNA
function, cell cycle and (programmed) cell death
• Transcription factors, gene expression, and epigenetics
• Protein modification, sorting, and membrane transport
• Receptors and signal transduction
• Basic techniques in Cell Biology (PCR, Electrophoresis, ELISA,
• Current models organisms in Cell Biology (e.g. E. coli, yeast, C.
elegans, drosophila, zebra fish, mammalian models)
• Visualization techniques in Cell Biology
Each student will also work on a literature assignment.
Teaching MethodsLectures (26h), work discussions related to the literature assignment
(6h), self-study in groups to repeat lecture material and for literature
Method of AssessmentWritten exam (2/3), literature assignment (1/3). Next to a minimum
combined grade of 6.0 for whole course a minimum grade of 5.0 is
required for the written exam and for the literature assignment.
LiteratureNo book mandatory. Useful books are:
Alberts et al. Molecular Biology of the Cell (more extensive,
recommended for Biomolecular track) or
Alberts et al. Essential Cell Biology (more concise, recommended for
We will also work with scientific literature. Examples: Kuhn Biol.
Chem. 2009, Bald & Koul FEMS Microbiol. Lett. 2010, Galperin et al.
Nucl. Acid Res. 2011.
Additional InformationCompulsory portal course Minor Biomolecular Sciences and Neurosciences.
This minor course requires a minimum of 25 participants to take place.
This course is offered in week 1-4 of period 1 and is to be taken
together with the accompanying course
Experimental Cell Biology II.
This course is based on first and second year level courses
in Cell Biology.
Recommended background knowledgeBasic (first and second year level) courses in Cell Biology
|Language of Tuition||English|
|Faculty||Faculty of Science|
|Course Coordinator||dr. D. Bald|
|Examiner||dr. D. Bald|
dr. D. Bald
dr. J.M. Kooter
dr. R.J.M. van Spanning
dr. S. Luirink
dr. J.P. van Ulsen
dr. J.R.T. van Weering
You need to register for this course yourself
Last-minute registration is available for this course.
|Teaching Methods||Study Group, Lecture, Practical|