Molecular Principles of Brain Disorders


Course Objective

Gain insight into the etiology, expression and treatment of various
brain diseases, as well as models used in preclinical science.

Course Content

Our brain enables us to perform even the most complex tasks. Sometimes
however, diseases of the brain compromise its optimal function. In this
course students learn what the clinical manifestations are of the
neurological and psychiatric diseases, and what type of cellular or
animal models are around to learn us more on how disturbed processes and
systems in the brain lead to these illnesses and that may provide us
with clues on treatment options. Various treatments options for these
conditions, including the use of pharmacological agents and deep brain
stimulation will be discussed.

In this course we will focus on different themes:
Theme 1: Neurodegenerative disorders (coordinator Dr. Wiep Scheper)
Theme 2: Psychiatric disorders (coordinator Dr. Hylke Vervaeke)

Next, you will be guided in writing a literature review.

Teaching Methods

Lectures (44 hours) and literature review (12 hours)

Course coordinators are Hylke Vervaeke and Wiep Schepers

Method of Assessment

Exam (Multiple Choice) (60%), literature study
(40%), each at least grade 5.5


Powerpoints from the lecture and extra literature on Canvas

Target Audience

Course in the track ‘Neurosciences’ in the minor ‘Biomolecular Sciences
and Neurosciences’.

Course in the minor 'Topics in Biomedical Sciences'

Additional Information

The track ‘Neurosciences’ is an excellent preparation for the Master

This minor course requires a minimum of 25 participants and a maximum of

This course is part of the Minor Neurosciences and the minor Topics in
Biomedical Sciences. Students from both minors have priority.

Custom Course Registration

Groups for literature review via Canvas

Recommended background knowledge

Basic (first and second year level) courses in Cell Biology and

General Information

Course Code AB_1049
Credits 6 EC
Period P2
Course Level 300
Language of Tuition English
Faculty Faculty of Science
Course Coordinator dr. H.K.E. Vervaeke
Examiner dr. H.K.E. Vervaeke
Teaching Staff dr. H.K.E. Vervaeke
dr. R.M. Meredith
dr. M.C. Schippers
dr. W. Scheper
R. Garritsen BA BSc

Practical Information

You need to register for this course yourself

Last-minute registration is available for this course.

Teaching Methods Computer lab, Study Group, Lecture, Practical