Course ObjectiveThe aim of the course is to increase knowledge and understanding of
biochemistry at a fundamental level and to develop a perspective on the
role of biochemistry in health and disease.
Course ContentContents of the course:
* Biochemical and molecular mechanisms by which cellular adhesion,
communication and signalling is regulated in the human body.
* Changes of these mechanisms in diseases with clinical examples of
congenital and acquired diseases such as heart and vascular diseases,
(chronic) infectious diseases, multiple sclerosis, alzheimer disease,
congenital disorders of glycosylation and cancer.
* Metabolic aspects of biochemistry are combined with their application
the diagnosis and monitoring of diseases, and the development of
therapies including drug design.
Teaching MethodsLectures (26-28h), learning in small groups (2h), laboratory course
(4h) and computer practica (8h); in addition, time for self-study is
included in the course.
Method of AssessmentWritten exam (90%). Participation in Laboratory course, computer
practicals Glycoworkbench and Drug design (10%)
are mandatory and will be assessed separately. A minimum of 5.50 for the
exam is required in order to pass.
Entry RequirementsBasic knowledge Biochemistry
Literature- Michael A Lieberman and Alan Marks: Basic Medical Biochemistry: A
Clinical Approach, 4th edition. ISBN: 978-1-45110-003-7.
- Essentials of Glycobiology:
http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=glyco2 (free internet
- Additional information & literature provided at the start of the
course on Canvas.
Target AudienceThe course provides an excellent basis for students which aim to focus
on medical biology (in particular immunology, infectious diseases and/or
oncology) in their master period.
dr. R. Fontijn, dr. J.J. Garcia Vallejo, dr.
ing. S.J. van Vliet, dr. J. Haanstra, dr.
E. Struijs, prof. dr. G. Salomons, dr. M. Wamelink,
dr. G. Kooij, prof. dr. J. van Horssen
This course is part of a minor with a limited number of participants.
Students taking the whole minor have priority.
Recommended background knowledgeBasic knowledge Immunology
|Language of Tuition||English|
|Faculty||Faculty of Science|
|Course Coordinator||drs. K. Brouwer|
|Examiner||J.J. Garcia Vallejo BSc|
drs. K. Brouwer
drs. ing. E.A. Struijs
drs. M.M.C. Wamelink
dr. ing. S.J. van Vliet
prof. dr. G.S. Salomons
J.J. Garcia Vallejo BSc
You need to register for this course yourself
Last-minute registration is available for this course.
|Teaching Methods||Computer lab, Study Group, Lecture, Practical|