Course Objective

• The student understands the basic structure and function of the
neuromuscular system as a model for neuronal communication and
• The student understands the relation between the electric
activity at nerve and muscle cell level and macroscopic
electrophysiological non-invasive EEG, MEG, and EMG measurements.
• The student understands the interpretation of the brain as a
dynamic network and can use basic computer simulation techniques to
interpret mechanisms.
• The student knows how to collect encephalographic data and to
interpret such data also in relation with external events.
• The student knows the important mechanisms behind central nervous
diseases and how these are reflected in abnormal brain activity.
• The student is confronted with neuromuscular disease states and
the diagnostic tools to do basic differential diagnostics.
• The student knows principles and applications of the most often
used techniques for (functional) brain imaging like (f)MRI, PET, TMS.

Course Content

This course will approach the function of the human nervous system from
different angles. Students will be familiarized with basic approaches to
neural communication and interaction. We then will deal with the
functional background of mass activity in the central nervous system.
The student will become familiar with the general principles of
electrophysiology and other neurophysiological imaging techniques. The
possible roles of oscillatory neuronal dynamics will be explained. The
use of relevant methods in the diagnostic process of central nervous
disorders and in the recent developments around brain-computer
interfaces will then be considered.

Teaching Methods

Lectures 17´2 hours, computer practical 3´4 hours, excursion (practical
Nijmegen) 1´4 hours. The course is build around three main themes: (i)
Neurons and neural network behavior, (ii) Signals from the brain and
their interpretation and (iii) Peripheral neuromuscular systems

Method of Assessment

2.75 hours (including dyslexia time); written exam with open questions

Entry Requirements

Basic knowledge and understanding of the neurophysiology of brain
processes and neuromuscular control concerning membrane potential, ion
channels, ion pumps, between neuron communication, function of different
brain structures, movement control, spinal cord circuits and motor
Knowledge of and skills in programming in Matlab at the level used in,
e.g., the FBW bachelor course ‘Meten van Fysische Grootheden’.


Research articles and lecture handouts will be provided before the

Custom Course Registration

For more info on workgroups, laboratories, (computer) practicals etc. please see Canvas.

General Information

Course Code B_NEUROSC
Credits 6 EC
Period P2
Course Level 400
Language of Tuition English
Faculty Fac. of Behavioural and Movement Science
Course Coordinator prof. dr. A. Daffertshofer
Examiner prof. dr. A. Daffertshofer
Teaching Staff prof. dr. A. Daffertshofer

Practical Information

You need to register for this course yourself

Teaching Methods Seminar, Lecture, Computer lab, Practical