Course Objective• The student understands the basic structure and function of the
neuromuscular system as a model for neuronal communication and
• The student understands the relation between the electric
activity at nerve and muscle cell level and macroscopic
electrophysiological non-invasive EEG, MEG, and EMG measurements.
• The student understands the interpretation of the brain as a
dynamic network and can use basic computer simulation techniques to
• The student knows how to collect encephalographic data and to
interpret such data also in relation with external events.
• The student knows the important mechanisms behind central nervous
diseases and how these are reflected in abnormal brain activity.
• The student is confronted with neuromuscular disease states and
the diagnostic tools to do basic differential diagnostics.
• The student knows principles and applications of the most often
used techniques for (functional) brain imaging like (f)MRI, PET, TMS.
Course ContentThis course will approach the function of the human nervous system from
different angles. Students will be familiarized with basic approaches to
neural communication and interaction. We then will deal with the
functional background of mass activity in the central nervous system.
The student will become familiar with the general principles of
electrophysiology and other neurophysiological imaging techniques. The
possible roles of oscillatory neuronal dynamics will be explained. The
use of relevant methods in the diagnostic process of central nervous
disorders and in the recent developments around brain-computer
interfaces will then be considered.
Teaching MethodsLectures 17´2 hours, computer practical 3´4 hours, excursion (practical
Nijmegen) 1´4 hours. The course is build around three main themes: (i)
Neurons and neural network behavior, (ii) Signals from the brain and
their interpretation and (iii) Peripheral neuromuscular systems
Method of Assessment2.75 hours (including dyslexia time); written exam with open questions
Entry RequirementsBasic knowledge and understanding of the neurophysiology of brain
processes and neuromuscular control concerning membrane potential, ion
channels, ion pumps, between neuron communication, function of different
brain structures, movement control, spinal cord circuits and motor
Knowledge of and skills in programming in Matlab at the level used in,
e.g., the FBW bachelor course ‘Meten van Fysische Grootheden’.
LiteratureResearch articles and lecture handouts will be provided before the
Custom Course RegistrationFor more info on workgroups, laboratories, (computer) practicals etc. please see Canvas.
|Language of Tuition||English|
|Faculty||Fac. of Behavioural and Movement Science|
|Course Coordinator||prof. dr. A. Daffertshofer|
|Examiner||prof. dr. A. Daffertshofer|
prof. dr. A. Daffertshofer
You need to register for this course yourself
|Teaching Methods||Seminar, Lecture, Computer lab, Practical|