Course ObjectiveThe aim of this course is to have an understanding of the major
methodological issues in designing a randomized controlled trial (RCT)
of a psychological intervention in mental health care. Students should
be able to identify strengths and weaknesses of the designs of published
trials and be able to design a trial themselves.
Course ContentThe course focuses on: the research questions which can be answered by
a RCT, types of RCTs, design of a RCT according to the CONSORT statement
(e.g. phrasing of the research question, choice of control group,
blinding, randomization, power analysis, in- and exclusion criteria,
measuring outcomes, treatment integrity),analyzing and presenting data
(including how to deal with missing data), and economical analyses.
Furthermore, we discuss medical ethical issues in performing a trial as
well as practical aspects of carrying out a RCT.
Teaching MethodsThere are lectures twice a week. The lectures consists of theory but
there are also small assignments as well as presentations by PhD
students running a RCT.
Method of AssessmentThere is an exam with open-end questions. Students also have to write a
research proposal of a RCT (pre-specified format). The exam weighs 2/3
and the paper 1/3 of the final grade. Both the exam and the paper have
to be sufficient (5.5 or higher).
LiteratureEveritt B.S. & Wessely S. (2008; 2nd edition) Clinical trials in
psychiatry. New York Oxford University press; journal papers (handed out
|Language of Tuition||English|
|Faculty||Fac. of Behavioural and Movement Science|
|Course Coordinator||prof. dr. A. van Straten|
|Examiner||prof. dr. A. van Straten|
prof. dr. A. van Straten
dr. A.M. Kleiboer
You need to register for this course yourself
|Teaching Methods||Lecture, Practical|