Course ObjectiveThe lectures and tutorials will provide insight into the basic
(bio-)chemical principles of the construction of living cells, the
chemical structure of the cellular components and the way in which
macromolecules (proteins, DNA, RNA, lipids) are used to make cells
function. Furthermore, the way in which signalling in and between cells
can takes place and how these pathways can be modulated by chemical
signalling substances and medicines will be discussed. Attention will be
given to how cells extract energy from the breakdown of nutrients and
how this energy is used for growth and cell division. Finally, the basic
principles of molecular biology of the living cell will be discussed.
All discussed aspects of cellular functioning will be placed in the
light of possible pathology that occurs when disorder takes place.
Course ContentWith the unraveling of the human genome and progress within the life
sciences we learn more and more about the role of different biomolecules
in important cellular processes. The course Biochemistry focuses on the
important components of cells and their function. Subjects to be
discussed are the different cell types, cell organelles, cellular
components (proteins, DNA / RNA and lipids) and the building blocks that
make up these macromolecules. Protein structure and function, signal
transduction and the metabolism (enzymes, Michaelis-Menten kinetics,
allosteric effects, metabolic / signal transduction pathways) will be
discussed as well. In particular, the protein molecules involved in
important cellular processes such as cellular communication, membrane
transport, cell division and apoptosis will receive attention. Where
possible attention will be paid to the way in which these processes can
lead to the development of diseases (including cancer, asthma,
Parkinson's) when disrupted.
Teaching MethodsLectures, tutorials, and self-study (slidecasts, books, canvas quizes).
Method of AssessmentOne partial exam and a final exam
LiteratureAlberts, B. e.a., Essential Cell Biology 5th ed, 2019
Target AudienceSecond year Mathematics students in the biomedical sciences track.
Recommended background knowledgeGenetics (AB_1135)
|Language of Tuition||English|
|Faculty||Faculty of Science|
|Course Coordinator||dr. S.J. Dekker|
|Examiner||dr. S.J. Dekker|
dr. S.J. Dekker
You need to register for this course yourself
Last-minute registration is available for this course.
|Teaching Methods||Seminar, Lecture|
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