Course Objective

To obtain detailed knowledge of radiopharmaceutical chemistry

Course Content

Radiopharmaceutical chemistry is the science of synthesising
radiopharmaceuticals for imaging techniques like Positron Emission
Tomography (PET) and Single Photon Emission Computed Tomography (SPECT)
or for therapeutic applications. The great clinical successes of nuclear
imaging and targeted radionuclide therapy have resulted in rapid growth
of the field of radiopharmaceutical chemistry, an essential component of
nuclear medicine. This course focusses on advanced radiopharmaceutical
chemistry, with key coverage of the chemistry that is required to
radiolabel compounds. The course will cover advanced radiochemistry of
11C, 13N, 15O, 18F, 89Zr, Iodine radionuclides as well as radiometals,
production of radionuclides, analysis techniques and radiation safety.

Teaching Methods

The "Flipped classroom method" is used. Lectures have been recorded
(slides + audio) and
need to be independently studied by the students (there are no regular
classes). Rather, all contact hours are used for problem solving
sessions and case studies.

Method of Assessment

Written examination(s)

Literature

Radiopharmaceutical Chemistry, Jason S. Lewis, Albert D. Windhorst,
Brian M. Zeglis, editors, Springer, 2019. ISBN 3319989464

Target Audience

mDDS, DD&S and D&I

Custom Course Registration

VUNet

Recommended background knowledge

organic chemistry or radiopharmaceutical chemistry or medicinal
chemistry or equivalent