Course ObjectiveObtaining insight into the molecular elements that form the basics for
structure and function of biomolecules. Also, gaining of knowledge about
the methods used to determine the structure and analyze the function of
Course ContentCentral to this course are molecular properties of structural elements
of DNA, lipids and proteins. The forces and interactions that determine
their structure, function and flexibility will be discussed. The basics
and applications of a number of techniques used to experimentally
determine macromolecular structures as well as techniques to visualize
dynamic structural changes will also be introduced. This includes
crystallization followed by X-ray diffraction, NMR spectroscopy and
electron microscopy. Also, the principles and applications of
computational structure determination (protein modeling) will be
Teaching MethodsLectures, self-study, assignments.
Method of AssessmentWritten Exam
LiteratureBranden, C., and Tooze, J., Introduction to Protein Structure, Garland,
Target Audience3F,3S, mi-AMPS
Additional InformationFor PyMOL exercieses install PyMOL Educational Version (limited to the
use within this course!) and bring a three button
computer mouse as a touchpad will not be sufficient.
Explanation CanvasLecture material as well as additional material will be published in
Recommended background knowledgeProject Cancer (MNW), Biochemistry Course (S/F/MNW).
|Language of Tuition||English|
|Faculty||Faculty of Science|
|Course Coordinator||dr. S. Hennig|
|Examiner||dr. S. Hennig|
dr. S. Hennig
dr. D.P. Geerke
You need to register for this course yourself
Last-minute registration is available for this course.
|Teaching Methods||Seminar, Lecture, Excursion|
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