Biochemistry in Health and Disease

Dit vak wordt in het Engels aangeboden. Omschrijvingen kunnen daardoor mogelijk alleen in het Engels worden weergegeven.

Doel vak

The aim of the course is to increase knowledge and understanding of
biochemistry at a fundamental level and to develop a perspective on the
role of biochemistry in health and disease.

Inhoud vak

Contents of the course:
* Biochemical and molecular mechanisms by which cellular adhesion,
communication and signalling is regulated in the human body.
* Changes of these mechanisms in diseases with clinical examples of
congenital and acquired diseases such as heart and vascular diseases,
(chronic) infectious diseases, multiple sclerosis, alzheimer disease,
congenital disorders of glycosylation and cancer.
* Metabolic aspects of biochemistry are combined with their application
the diagnosis and monitoring of diseases, and the development of
therapies including drug design.


Lectures (26-28h), learning in small groups (2h), laboratory course
(4h) and computer practica (8h); in addition, time for self-study is
included in the course.


Written exam (90%). Participation in Laboratory course, computer
practicals Glycoworkbench and Drug design (10%)
are mandatory and will be assessed separately. A minimum of 5.50 for the
exam is required in order to pass.

Vereiste voorkennis

Basic knowledge Biochemistry


- Michael A Lieberman and Alan Marks: Basic Medical Biochemistry: A
Clinical Approach, 4th edition. ISBN: 978-1-45110-003-7.
- Essentials of Glycobiology: (free internet
- Additional information & literature provided at the start of the
course on Canvas.


The course provides an excellent basis for students which aim to focus
on medical biology (in particular immunology, infectious diseases and/or
oncology) in their master period.

Overige informatie

dr. R. Fontijn, dr. J.J. Garcia Vallejo, dr.
ing. S.J. van Vliet, dr. J. Haanstra, dr.
E. Struijs, prof. dr. G. Salomons, dr. M. Wamelink,
dr. G. Kooij, prof. dr. J. van Horssen

This course is part of a minor with a limited number of participants.
Students taking the whole minor have priority.

Aanbevolen voorkennis

Basic knowledge Immunology

Algemene informatie

Vakcode AB_1054
Studiepunten 6 EC
Periode P2
Vakniveau 300
Onderwijstaal Engels
Faculteit Faculteit der Bètawetenschappen
Vakcoördinator drs. K. Brouwer
Examinator J.J. Garcia Vallejo BSc
Docenten drs. K. Brouwer
drs. ing. E.A. Struijs
drs. M.M.C. Wamelink
dr. ing. S.J. van Vliet
prof. dr. G.S. Salomons
J.J. Garcia Vallejo BSc

Praktische informatie

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Werkvormen Hoorcollege, Werkgroep, Computerpracticum, Practicum