Infectious Diseases

Dit vak wordt in het Engels aangeboden. Omschrijvingen kunnen daardoor mogelijk alleen in het Engels worden weergegeven.

Doel vak

The aim of this course is to provide the student with insight into the
mechanisms of microbial and parasitic infections down to the molecular
level. The student is introduced to the strategies that bacteria,
viruses, parasites and fungi use to colonize and infect the host. The
topics covered are toxins, adhesion, invasion, intracellular survival,
interactions with the immune system and regulation and transfer of
virulence factors. In addition, attention is paid to vaccines and
antibiotics, such as the development, working mechanisms and application
of these therapeutics. Finally, the student must be able to apply a
number of microbiological methods in order to study the pathogenic
properties of microorganisms.

At the end of the course the student can:
- indicate the similarities and differences in the strategies that
bacteria, viruses, fungi and parasites use to colonize and infect the
- describe how vaccines and antibiotics work at the molecular level.
- indicate how vaccines and antibiotics are developed.
- indicate the importance of a thorough knowledge of the virulence
factors of bacteria, viruses, fungi and parasites to prevent and combat

Inhoud vak

The course consists of 6 parts: bacteriology, parasitology, virology,
mycology, vaccinology and antibiotics. All these components are
necessary to gain a solid understanding of infectious diseases and how
they can be prevented and controlled. Attention will therefore be paid
to the coherence of the above components.


Lectures (24 hours); practical part, compulsory (40 hours); self-study
(104 hours). N.B. A large part of the material in the textbook is not
discussed in the lectures and must therefore be learned entirely by
means of self-study.

Involved teachers:
dr. E.N.G. Houben, dr. M. Bergman, dr. P. van Ulsen, prof. W. Bitter,
dr. M. van Dijk, dr. B. Krom


Written exam (combination of multiple choice and essay questions) in
English. The use of a dictionary -without personal notes- is permitted.
Admission to the exam is only possible if the practical part has been
completed successfully.

Vereiste voorkennis

Students BSc Biomedical Sciences (BMS) need to have passed the first
year course Microbiology - toxicology (AB_1139) and Immunology
Students BSc G&L need to have passed the courses Microbiology (AB_1146)
and Cell biology and immunology (AB_1132).
Students Biology need to have successfully completed the second year
courses The microbial cell (AB_470201) and Regulation and defense in
animals (AB_470202)

The material from the above mentioned courses will come back during the
course and is assumed to be known at the time of the examination.


Book: Microbiology A clinical approach; Strelkauskas, Edwards, Fahnert,
Pryor and Strelkauskas, 2nd edition. Garland Science. ISBN:
Practical manual (purchase compulsory, price about 10 euros).


Optional course for third year BSc Biomedical Sciences and second or
third year BSc Health and Life with the biomedical or clinical major.
The course is recommended for students who want to take the Infectious
Diseases specialization in the 2-year MSc Biomedical Sciences.

Overige informatie

Presence required for all practical days. A lab coat is also compulsory
and is already needed on the first day of the practical part.

Afwijkende intekenprocedure

There is a maximum of 76 students for this course; this is the maximal number of students that can participate in the practical part. BSc students Biomedical Sciences and Health & Life are given priority. This can mean that registered students from other programmes are rejected. Admission to the course is based on the order of registration via VUnet. Students of Health Sciences should register for the course Infectious diseases: host-pathogen interactions (AB_1174). IMPORTANT: Returning students (students that have completed the practical part of the course in previous years but still need to pass the written exam) are urged to register exclusively for the exam and not for the lectures and practical part, so that no practical places is reserved for them. They can access Canvas by sending an email to the course coordinator ( In addition, students who initially enrolled, but at some point decide not to take the course anymore, are urged to leave the course and to report this in an email to the course coordinator (

Algemene informatie

Vakcode AB_471024
Studiepunten 6 EC
Periode P6
Vakniveau 300
Onderwijstaal Engels
Faculteit Faculteit der Bètawetenschappen
Vakcoördinator dr. E.N.G. Houben
Examinator dr. E.N.G. Houben
Docenten dr. B.P. Krom
dr. M.P. Bergman
dr. E.N.G. Houben
prof. dr. W. Bitter
dr. J.P. van Ulsen

Praktische informatie

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Werkvormen Hoorcollege, Practicum*

*Voor deze werkvorm kun je geen groep kiezen, je wordt hiervoor ingedeeld.