Cancer-Immunity-Personalized therapies

Dit vak wordt in het Engels aangeboden. Omschrijvingen kunnen daardoor mogelijk alleen in het Engels worden weergegeven.

Doel vak

1. Genetic, vascular and immune (dys) functioning in health and disease
2. Interaction between host and pathogen
3. Diagnosing cancer and other immune mediated diseases in early phases
4. Using the immune system to treat cancer
5. The role of imaging in diagnosis, targeted treatment, and monitoring
of patients

Inhoud vak

This minor addresses various immune-related processes that play a
crucial role in almost every disease. It is often the balance within the
immune system that determines the outcome of disease, ranging from
tissue destruction or the development of cancer to complete cure. To
illustrate this point, we will touch upon immunological reactions that
are out of balance, resulting in chronic inflammatory diseases. On the
other hand, lack of immunity due to specific molecular deficiencies can
result in cancer. The latest achievements in the field of cancer
treatment by immune therapy will be highlighted. Also, this minor will
give insight in the ongoing battle between a host and its pathogens.
To reach these aims, the minor addresses the latest diagnostic
techniques in order to understand the underlying pathophysiology: these
techniques include genome-wide DNA and RNA sequencing, metabolomics and
microbiome analysis.
The minor is completed with the new role of Medical Imaging and
Nanomedicine in the context of personalized therapy. Patients are
different in their genetic DNA profile, immune system, microbiome and
metabolism, so if possible, treatment should be optimized by accounting
for these personal characteristics. You will learn advanced imaging
techniques such as Nuclear Medicine and MRI, which are used to assess if
your patient is responding to the given therapy.
All these aspects will be covered by (pre)clinical and scientific
experts in their own field.


Lectures, practicals, working groups


Writing assignment, research proposal writing, oral presentation,
debate, two central exams. (min. 5 independent exams)


Bachelor’s students of VUmc School of Medical Sciences and external (and
international) students with a (bio)medical background.

Toelichting Canvas

This minor is supported by a corresponding CANVAS course, which contains
all of the required information of this minor including an overview of
the required articles and assignments. The CANVAS course will also be
used to post announcements relevant to the minor. You will automatically
have access to the CANVAS course.

Aanbevolen voorkennis

Knowledge on Immunology, Pathology and Microbiology is recommended.

Algemene informatie

Vakcode M_BCIPT19
Studiepunten 24 EC
Periode Semester 1
Vakniveau 300
Onderwijstaal Engels
Faculteit VUmc
Vakcoördinator prof. dr. R.E. Mebius
Examinator prof. dr. R.E. Mebius
Docenten prof. dr. R.E. Mebius
S. Nezhentsev MA

Praktische informatie

Voor dit vak kun je niet zelf intekenen; het onderwijsbureau van jouw faculteit tekent je in.

Werkvormen Werkcollege, Studiegroep, Practicum

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