Major Research Project Theoretical Chemistry (C, E, S)

Dit vak wordt in het Engels aangeboden. Omschrijvingen kunnen daardoor mogelijk alleen in het Engels worden weergegeven.

Doel vak

The aim is to obtain experience in scientific research including the
design and execution of computational experiments and to critically
interpret and reflect on these results. The project will be conducted
within the field of theoretical (bio)chemistry in one of the following
- University or Academic hospital
- Research institute
- Company
The internship can be performed either within the Netherlands or abroad.

Inhoud vak

The specific content of the project depends on the associated
supervisor(s), available projects at the host/location and the timing of
the internship, but generally deals with quantum chemical methods,
including Density Functional Theory (DFT). DFT calculations are used to
gain insights in chemical interactions, like reaction mechanisms that
lead to the synthesis of drugs, or the interactions of (drug) molecules
with DNA and/or proteins.

Attention will be paid to setting up new research/experiments, using
state-of-the-art computational techniques, analyzing computational
results and keeping adequate documentation.


Literature review, formulating a research question, conducting
experiments, keeping adequate documentation, analyzing data, reporting
on results in progress/group meetings, in a written thesis and final
presentation within the research group.


Academic attitude, execution, oral presentation, and written thesis

Vereiste voorkennis

Entry requirements with respect to attained courses and number of
credits apply. See the Education and Examination regulations and the
internship manual Drug Discovery & Safety. For questions, consult the
internship coordinator well in advance (


Starting literature will be provided by the supervisor. The first 1-2
weeks of the traineeship will be spent on literature reading and
preparation for the project.


C,E,S variants of mDDS-CMCT, mDDS-DD&S

Overige informatie

The standard length of a major internship for the Communication,
Education, or Societal variant is 24 EC (4 months), which can be
extended tot 36 EC (6 months). Make sure you discuss your personal
education plan with your master coordinator well in advance. See the
“Master Drug Discovery & Safety Internship manual” for more information
(rules, regulations, tips, etc.) on the internship process. This manual
can be found on the canvas community “Master Drug Discovery & Safety”.

Afwijkende intekenprocedure

The number of internal (VU) internship positions is limited. Candidates are selected based on their motivation letter and CV in an application procedure. See the canvas site “Master Drug Discovery & Safety” for more information regarding this application procedure. Be aware that selection procedures exist for most external positions as well. Before the start of the project an internship agreement has to be signed by all involved parties and the project proposal has to be approved by the VU supervisor. See the “Master Drug Discovery & Safety Internship manual” for more information on the rules and regulation regarding internships. If after reading the manual you still have questions regarding the process related to internships, admission, approval, etc., please contact the internship coordinator via

Algemene informatie

Vakcode XM_0029
Studiepunten 24 EC
Periode Ac. Jaar (sept)
Vakniveau 600
Onderwijstaal Engels
Faculteit Faculteit der Bètawetenschappen
Vakcoördinator dr. D.J. Scholten
Examinator dr. D.J. Scholten

Praktische informatie

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