Drug Action

2018-2019
Dit vak wordt in het Engels aangeboden. Omschrijvingen kunnen daardoor mogelijk alleen in het Engels worden weergegeven.

Doel vak

To obtain a general introduction into and deepening of knowledge of
fundamental principles and molecular aspects of drug action within the
field of molecular pharmacology and receptor biochemistry.

Inhoud vak

Most drugs display their pharmacological actions following the
interactions with receptor proteins. As for the molecular
pharmacological aspects the mechanisms by which these drugs act with
respect to their therapeutic application will be studied. Novel concepts
of pharmacology, including constitutive receptor activity, allosteric
modulation, receptor dimerization and ligand-biased signaling will be
addressed. Important cellular and animal model systems used to
investigate (pathological and pharmacological) aspects of cell biology
in relation to drug discovery will be discussed.

Onderwijsvorm

Lectures, exercises, case-studies

Toetsvorm

Written examination(s) and assignments.

Literatuur

Pharmacology in Drug Discovery and Development 2nd edition - T.P.
Kenakin
eBook ISBN: 9780128037539
Paperback ISBN: 9780128037522

Scientific papers (primary and review) provided during the course

Doelgroep

mDDS

Aanbevolen voorkennis

Knowledge of basic principles of drug action and mathematics (i.e.
re-arranging formulas and understanding of (non)linear equations).

Algemene informatie

Vakcode X_432724
Studiepunten 6 EC
Periode P3
Vakniveau 400
Onderwijstaal Engels
Faculteit Faculteit der Bètawetenschappen
Vakcoördinator dr. H.F. Vischer
Examinator dr. H.F. Vischer
Docenten dr. H.F. Vischer

Praktische informatie

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Werkvormen Hoorcollege
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