Basic Models of Biological Networks

2019-2020
Dit vak wordt in het Engels aangeboden. Omschrijvingen kunnen daardoor mogelijk alleen in het Engels worden weergegeven.

Doel vak

The aim of the course is to learn the basis of modelling of biological
systems. Computer models of metabolic networks, signal transduction
pathways and transcriptional regulation are becoming indispensible in
modern (medical) biology. After this course, students have an
understanding of the principles of modelling, have learned to work with
modelling tools and have applied these tools to biological examples.
This should provide enough background for students to communicate with
modellers or read modelling papers.

Inhoud vak

In this course we will teach how to set up computer models of biological
systems, and how such models can be programmed in common software tools.
We will provide some basic theoretical concepts required for
understanding how to make models and how to interpret the results.
Topics will include: properties of cell components (such as enzyme
kinetics), mass and energy balances, stoichiometry and constraint-based
modelling, kinetic modelling, Metabolic Control Analysis, modelling
software. Topics will be illustrated by computer practicals of
biological examples.

Onderwijsvorm

Lectures, self-study, computer practical work, computer modelling
tutorials

Toetsvorm

Results of computer assignments, written exams.

Literatuur

A course syllabus with recent reviews and papers presented by the
lecturers and guest researchers (max. 15 euros).

Algemene informatie

Vakcode X_418154
Studiepunten 6 EC
Periode P2
Vakniveau 500
Onderwijstaal Engels
Faculteit Faculteit der Bètawetenschappen
Vakcoördinator prof. dr. F.J. Bruggeman
Examinator prof. dr. F.J. Bruggeman
Docenten prof. dr. F.J. Bruggeman
dr. J.P. Bruggeman

Praktische informatie

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Werkvormen Werkcollege, Hoorcollege, Computerpracticum
Doelgroepen

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