Biomedical Modelling and Simulation

2019-2020
Dit vak wordt in het Engels aangeboden. Omschrijvingen kunnen daardoor mogelijk alleen in het Engels worden weergegeven.

Doel vak

To gain knowledge of the most important theoretical and practical
concepts in modelling and simulation of biomedical processes at
different scales, ranging from macroscopic organ function, cellular
function down to biochemical interactions and signaling pathways within
cells.

To gain experience with and to apply MatLab and Mathematica to acquire,
analyse and evaluate biomedical signals and to model and simulate
biomedical processes.

Inhoud vak

This course will start with a general overview the various types of
models used to describe biomedical processes by parametric and
non-parametric models using linear and non linear (differential)
equations. Basic knowledge of vector and matrix calculations and
differential equations is required but will be refreshed.

During the course, attention will be paid to viscoelastic models,
spectral analysis, compartment models, geometric modelling used in image
analysis and models to describe molecular structures and their dynamic
behaviour.

Examples will concentrate on cardiovascular function: linear and
nonlinear
viscoelastic models of pressure volume relations, compartment models of
the interaction between contractile proteins to simulate force and
pressure development and a description of an ion pump for instance to
import Ca-ions into the cell during an action potential.

The introductory lectures will be combined and followed by practical
courses in which, through exercises, experience will be gained of
MatLab and Mathematica (4th generation computer languages). Finally
students will be offered a choice of 1 out of 5 modelling problems to
be solved in small groups, guided by a supervisor. At
the end of the course each group will present and discuss their work
with all participants and supervisors of the course.

Onderwijsvorm

Lectures, working groups, assignments.

Toetsvorm

Assignments (20%), report and presentation on modelling problem (40%)
and written exam (40%).

Literatuur

Syllabus.
Book (recommended): Gilat, A., MatLab: An Introduction with
Applications, 5th ed, Wiley.

Doelgroep

mCh-SBI, mMNS-MPs, mMNS-PoL, mMNS-MPy, mPhys-BB, mPhys-SBI

Algemene informatie

Vakcode X_430112
Studiepunten 6 EC
Periode P1
Vakniveau 400
Onderwijstaal Engels
Faculteit Faculteit der Bètawetenschappen
Vakcoördinator dr. I.H.M. van Stokkum
Examinator dr. I.H.M. van Stokkum
Docenten dr. ir. T.J.C. Faes
dr. I.H.M. van Stokkum

Praktische informatie

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Werkvormen Werkcollege, Hoorcollege, Werkgroep, Practicum
Doelgroepen

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